Product Details
Factory Sells Best Quality Hexamethyldisilazane (HMDS) 999-97-3 with USP
Hexamethyldisilazane/HMDS CAS No.999-97-3
Product details
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Chemical Name: |
Hexamethyldisilazane |
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CAS No.: |
999-97-3 |
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EINECS No.: |
213-668-5 |
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Empirical Formula: |
C 6 H 19 NSi 2 |
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Color and Appearance: |
Clear Transparent liquid |
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Purity: |
99% by GC |
Applications
It can be used to introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as alcohols, carboxylic acids, amines etc. The most common industrial application is in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin.
The usual procedure is to protect the carboxylic group in the antibiotic with HDMS followed by acylation with the desired acylchloride. Finally, desilylation under mild aqueous conditions gives the desired product.
Package: 150kg/Iron drum or 750kg/IBC drum
Hexamethyldisilazane is a colorless and transparent liquid with two methyl groups attached to silicon atoms and bridged by nitrogen atoms. HMDS is a commonly used silane coupling agent that can form chemical bonds with various materials, enhancing their adhesive properties and stability. It is used as a crosslinking agent or surface treatment agent in the manufacturing of rubber, plastic, coatings, and composite materials, as well as for silane treatment to improve the water resistance and chemical resistance of materials.
